Complications in Pregnancy of Sickle Cell Disease

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Pregnancy and the skeletal complications of sickle cell disease.

Introduction Sickle cell anaemia (HbSS) and sickle cell haemoglobin-C disease (HbSC) are the varieties of sickle cell disease usually encountered during pregnancy in Nigeria (Akinla, 1972). The incidence, though low, is certainly increasing. This is because young girls with a chronic haemolytic anaemia who in the past readily succumbed to intercurrent disease and malnutrition are now, with impr...

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Intracardiac Thrombosis in Sickle Cell Disease

In patients with sickle cell disease, thrombotic microangiopathy is a rare complication. Also in sickle cell disease, intracardiac thrombus formation without structural heart diseases or atrial arrhythmias is a rare phenomenon. We herein describe a 22-year-old woman, who was a known case of sickle cell-βthalassemia, had a history of recent missed abortion, and was admitted with a vaso-occlusive...

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Psychological complications in sickle cell disease.

This review examines the evidence for some of the common psychological complications found across the life span of patients with sickle cell disease (SCD), which are likely to be encountered by haematologists responsible for their medical management. Electronic searches of medical and psychological databases were conducted with a focus on three main areas: psychological coping, quality of life ...

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[Acute complications in sickle cell disease].

Sickle cell disease is an inherited disease characterised by the presence of an abnormal haemoglobin. Sickle cell disease can be complicated by acute vaso-occlusive crisis, which are the major clinical problem prompting admission to hospital and the major cause of death. It mainly manifests by osteo-articular pain and acute chest syndrome and can be complicated by multi-organ failure. The main ...

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Nephrotic syndrome, sickle-cell disease and pregnancy.

A young West Indian with sickle-cell disease and the nephrotic syndrome in the last trimester of pregnancy was treated after admission to hospital with folic acid and blood transfusion. Labour was induced by intravenous prostaglandin E2 but the fetus died. The nephrotic syndrome resolved but the proteinuria, the cause of which it is suggested is a true sickle-cell nephropathy, persisted.

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ژورنال

عنوان ژورنال: Blood

سال: 2020

ISSN: 0006-4971,1528-0020

DOI: 10.1182/blood-2020-138470